Hulscher reviewed genetic vaccine platforms he said are used or under development in poultry, farmed fish, swine, ducks, and cattle, including recombinant herpesvirus vectors, plasmid DNA, RNA replicon particles, conventional mRNA-LNP, and self-amplifying RNA. He argued that food-safety assessment has not adequately measured what platform components or expressed antigens reach edible tissues, survive slaughter, cooking and digestion, or become orally bioavailable to consumers, and he cited a 2018 CFIA environmental assessment as evidence that special human-safety monitoring was not planned. He also discussed biodistribution findings, the absence of exposure classification and human-outcome surveillance, and consumer disclosure. His recommendations included tissue-residue and oral-bioavailability studies, retail surveillance, stratified intake assessment, a moratorium on further authorizations pending study, exposure tracking, point-of-sale disclosure, and a reporting pathway for possible human food-safety signals.
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